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Combining Private Enterprise

with Academic Excellence


The Toxicology Research Laboratory has performed efficacy testing in a wide range of animal models and continues to develop new models based on client needs.  The team of researchers involved in the development of efficacy models collaborates with experts in the particular discipline, which makes these collaborations seamless and efficient for our clients.  Efficacy models are available in multiple species, including mice, rabbits, dogs, ferrets, minipigs, and non-human primates.  Efficacy models previously developed at TRL include:


         - Acute Radiation Syndrome (ARS) in mice, mini-pigs and NHPs

         - Mucositis

         - Diabetes models

         - Dental plaque and gingivitis

         - Hair growth

         - Collagen Induced Arthritis (CIA) Model in mice


The Toxicology Reserach Laboratory's scientific and regulatory staff is committed to provide whole animal model systems to evaluate the efficacy of potential therapeutic agents following human xenograft tumor models.

         -  Lung Cancer Xenograft Model

         -  Prostate Cancer Xenograft

         -  Breast Cancer Xenograft Model

         -  Colon Cancer Xenograft Model

         -  Pancreatic Cancer Xenograft Model

         -  Transgenic Cancer Models (e.g., TRAMP, LADY, etc.)

         - Chemically Induced Liver Cancer Model




Efficacy Studies