ANALYTICAL / BIOANALYTICAL SERVICES

The Analytical and Bioanalytical division of TRL provides GLP Compliant analytical chemistry support for all non-clinical studies.  Equipped with the latest technologies, including LC-MS/MS, HPLC, Atomic Absorption, ELISA, and MSD, our professional staff is proactive in meeting client needs as they expand our current capabilities.  Our experienced staff develops and validates quantitative methods for traditional, small-molecule therapeutics, as well as novel biotechnology-derived macromolecules, to provide our clients with quality results, timely delivery, and responsive support.

Analytical and Bio analytical Services include:

• Development of qualitative and quantitative analytical HPLC, LC/MS or LC-MS/MS methods for different compounds and drugs in support of pre clinical drug discovery studies.
• Analytical support for pharmacokinetics studies, dose formulation and dose verification, metabolite identification, stability, solubility, and other ex perimental needs.
• Development and qualification/validation of ELISA and MSD methods of quantification of macromolecules, including biomarkers.
• In vitro metabolic profiling utilizing microsomes, S9 and hepatocytes for mice, rats, dogs, monkeys and human