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  • TRL SERVICES
    • General Toxicology
    • Pharmacokinetics
    • Safety Pharmacology
    • Reproductive Toxicology
    • Genotoxicity
    • ADME Studies
    • Efficacy Studies
    • Analytical/Bio Services
    • Acute Radiation Models
  • REQUEST A STUDY
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PHARMACOKINETICS

Our dedicated Pharmacokinetics group works closely with other operational departments to provide pharmacokinetic data for our preclinical studies, FDA Animal Rule studies, and veterinary clinical studies in a timely fashion. Utilizing industry-standard WinNonlin® system that was validated according to GLP requirements, the following types of study designs are provided:

• Non-compartmental pharmacokinetics
• Compartmental pharmacokinetics/simulations
• Ascending dose (assessment of dose proportionality)
• Repeat dose (assessment of multiple dose linearity)
• Bioavailability and bioequivalence
• Drug interaction studies
• Special populations
• Pharmacodynamic and PK/PD modeling
• Deconvolution

We offer preclinical pharmacokinetics in multiple species:

• Mice
• Rats (cannulated for serial sampling or sparse sampling)
• Rabbits
• Dogs
• Minipigs
• Non-Human Primates 

  • General Toxicology
  • Pharmacokinetics
  • Safety Pharmacology
  • Reproductive Toxicology
  • Genotoxicity
  • ADME Studies
  • Efficacy Studies
  • Analytical/Bio Services
  • Acute Radiation Models

TOXICOLOGY RESEARCH LABORATORY

808 S Wood St Chicago IL 60612

773-406-6380

Copyright © 2025 TOXICOLOGY RESEARCH LABORATORY - All Rights Reserved.

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